The microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner

The microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner

Protein phosphatase1 (PP1), a signalling and transcriptional regulator, and epigenetic modulator is known to be a memory suppressor. Here the authors show that memory control by PP1 involves the microRNA cluster miR-183/96/182, and that this cluster is selectively regulated during memory formation i...

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Bibliographic Details
Main Authors: Bisrat T. Woldemichael, Ali Jawaid, Eloïse A. Kremer, Niharika Gaur, Jacek Krol, Antonin Marchais, Isabelle M. Mansuy
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12594
Description
Summary:Protein phosphatase1 (PP1), a signalling and transcriptional regulator, and epigenetic modulator is known to be a memory suppressor. Here the authors show that memory control by PP1 involves the microRNA cluster miR-183/96/182, and that this cluster is selectively regulated during memory formation in mice.
ISSN:2041-1723

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