Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation

Tranexamic acid (TXA) has been used to manage menstrual bleeding and reduce bleeding during orthopedic procedures, but has not been widely used in urology. We present a patient with refractory gross hematuria with required therapeutic anticoagulation who failed multiple other measures to control pro...

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Main Authors: Brian Le, Margaret Knoedler, Gray Roberge
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Urology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442019300993
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spelling doaj-5814a943c7b646218892ea677a1296e82020-11-25T01:29:43ZengElsevierUrology Case Reports2214-44202020-01-0128Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulationBrian Le0Margaret Knoedler1Gray Roberge2University of Wisconsin-Madison, Department of Urology, 1685 Highland Avenue, 3rd Floor, Madison, WI, 53705, USAUniversity of Wisconsin-Madison, Department of Urology, 1685 Highland Avenue, 3rd Floor, Madison, WI, 53705, USACorresponding author.; University of Wisconsin-Madison, Department of Urology, 1685 Highland Avenue, 3rd Floor, Madison, WI, 53705, USATranexamic acid (TXA) has been used to manage menstrual bleeding and reduce bleeding during orthopedic procedures, but has not been widely used in urology. We present a patient with refractory gross hematuria with required therapeutic anticoagulation who failed multiple other measures to control prostatic bleeding. This patient's hematuria abated with endoscopic localized injection of tranexamic acid into the prostate. The effects were durable with no bleeding recurrence reported while maintaining therapeutic anticoagulation.http://www.sciencedirect.com/science/article/pii/S2214442019300993
collection DOAJ
language English
format Article
sources DOAJ
author Brian Le
Margaret Knoedler
Gray Roberge
spellingShingle Brian Le
Margaret Knoedler
Gray Roberge
Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
Urology Case Reports
author_facet Brian Le
Margaret Knoedler
Gray Roberge
author_sort Brian Le
title Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_short Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_full Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_fullStr Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_full_unstemmed Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_sort intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
publisher Elsevier
series Urology Case Reports
issn 2214-4420
publishDate 2020-01-01
description Tranexamic acid (TXA) has been used to manage menstrual bleeding and reduce bleeding during orthopedic procedures, but has not been widely used in urology. We present a patient with refractory gross hematuria with required therapeutic anticoagulation who failed multiple other measures to control prostatic bleeding. This patient's hematuria abated with endoscopic localized injection of tranexamic acid into the prostate. The effects were durable with no bleeding recurrence reported while maintaining therapeutic anticoagulation.
url http://www.sciencedirect.com/science/article/pii/S2214442019300993
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AT grayroberge intraprostaticinjectionoftranexamicacidtocontrolrefractorybleedingwhilemaintainingtherapeuticanticoagulation
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