Application of CRISPR/Cas9 system in virus research

Application of CRISPR/Cas9 system in virus research

To date, the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system has been widely used to edit the genome in many species and cells. The system is the third generation of artificial endonuclease, which can edit DNA by recognizing short DNA sequences. This paper reviews the s...

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Bibliographic Details
Main Authors: ZHENG Qingfen, DUAN Zhongping, LI Jiansheng
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2016-01-01
Series:Linchuang Gandanbing Zazhi
Subjects:
virus
RNA editing
review
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=7130
id doaj-580a67ee86b94dbfa1b0a5f5c89b175c
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spelling doaj-580a67ee86b94dbfa1b0a5f5c89b175c2020-11-24T22:44:49ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562016-01-0132118518710.3969/j.issn.1001-5256.2016.01.041Application of CRISPR/Cas9 system in virus researchZHENG Qingfen0DUAN Zhongping1LI Jiansheng2The First Affiliated Hospital of Zhengzhou UniversityThe First Affiliated Hospital of Zhengzhou UniversityThe First Affiliated Hospital of Zhengzhou UniversityTo date, the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system has been widely used to edit the genome in many species and cells. The system is the third generation of artificial endonuclease, which can edit DNA by recognizing short DNA sequences. This paper reviews the structural features of the system and its application in virus research, such as the functional studies of virus-related genes and the exploration of antiviral therapies (including HIV, HBV, and EB virus), looking forward to the future direction of virus research.http://www.lcgdbzz.org/qk_content.asp?id=7130virusRNA editingreview
collection DOAJ
language zho
format Article
sources DOAJ
author ZHENG Qingfen
DUAN Zhongping
LI Jiansheng
spellingShingle ZHENG Qingfen
DUAN Zhongping
LI Jiansheng
Application of CRISPR/Cas9 system in virus research
Linchuang Gandanbing Zazhi
virus
RNA editing
review
author_facet ZHENG Qingfen
DUAN Zhongping
LI Jiansheng
author_sort ZHENG Qingfen
title Application of CRISPR/Cas9 system in virus research
title_short Application of CRISPR/Cas9 system in virus research
title_full Application of CRISPR/Cas9 system in virus research
title_fullStr Application of CRISPR/Cas9 system in virus research
title_full_unstemmed Application of CRISPR/Cas9 system in virus research
title_sort application of crispr/cas9 system in virus research
publisher Editorial Department of Journal of Clinical Hepatology
series Linchuang Gandanbing Zazhi
issn 1001-5256
1001-5256
publishDate 2016-01-01
description To date, the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system has been widely used to edit the genome in many species and cells. The system is the third generation of artificial endonuclease, which can edit DNA by recognizing short DNA sequences. This paper reviews the structural features of the system and its application in virus research, such as the functional studies of virus-related genes and the exploration of antiviral therapies (including HIV, HBV, and EB virus), looking forward to the future direction of virus research.
topic virus
RNA editing
review
url http://www.lcgdbzz.org/qk_content.asp?id=7130
work_keys_str_mv AT zhengqingfen applicationofcrisprcas9systeminvirusresearch
AT duanzhongping applicationofcrisprcas9systeminvirusresearch
AT lijiansheng applicationofcrisprcas9systeminvirusresearch
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