QSPR Studies on Aqueous Solubilities of Drug-Like Compounds

QSPR Studies on Aqueous Solubilities of Drug-Like Compounds

A rapidly growing area of modern pharmaceutical research is the prediction of aqueous solubility of drug-sized compounds from their molecular structures. There exist many different reasons for considering this physico-chemical property as a key parameter: the design of novel entities with adequate a...

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Bibliographic Details
Main Authors:	Eduardo A. Castro, Pablo R. Duchowicz
Format:	Article
Language:	English
Published:	MDPI AG 2009-06-01
Series:	International Journal of Molecular Sciences
Subjects:	QSPR theory aqueous solubility ADME/Tox properties Lipinski rules molecular descriptors replacement method group contribution methods high throughput screening techniques
Online Access:	http://www.mdpi.com/1422-0067/10/6/2558/

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