Mice as Animal Model for Evaluation of Therapeutic Efficacy of Preparations against Monkeypox

Mice as Animal Model for Evaluation of Therapeutic Efficacy of Preparations against Monkeypox

of MPV after 7 days postinfection, applying peroral administration once within 24 hours (24 hours before infection and 7 days after infection of mouse with 60 µg/g of a preparation). Displayed is the feasibility of using 8–15-days-old ICR mice (body weight 9–11 g) as an animal model for evaluation o...

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Bibliographic Details
Main Authors: Al. A. Sergeev, A. S. Kabanov, L. E. Bulychev, O. V. P’Yankov, Ar. A. Sergeev, O. S. Taranov, S. A. Bodnev, Yu. V. Tumanov, L. N. Shishkina, A. P. Agafonov, A. N. Sergeev
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2013-06-01
Series:Проблемы особо опасных инфекций
Subjects:
вирус оспы обезьян
мышь
интраназальное инфицирование
50 % инфицирующая доза
клинические признаки
противооспенные препараты
модельное животное
monkeypox virus
mouse
intranasal infection
50 % infective dose
clinical signs
preparations against monkeypox
animal model
Online Access:https://journal.microbe.ru/jour/article/view/34

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