Single- and multiple-dose pharmacokinetics of ethambutol and rifampicin in a tuberculosis patient with acute respiratory distress syndrome undergoing extended daily dialysis and ECMO treatment
The dosing of drugs in critically ill patients undergoing renal replacement therapy is based on limited data. We report for the first time single- and multiple-dose pharmacokinetics of ethambutol (EMB), which is cleared renally to 80%, and rifampicin (RIF), which is cleared renally to <30%, in a...
Main Authors: | Ann-Kathrin Strunk, Sandra Ciesek, Julius J. Schmidt, Christian Kühn, Marius M. Hoeper, Tobias Welte, Jan T. Kielstein |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-01-01
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Series: | International Journal of Infectious Diseases |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971215002520 |
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