Expression variation: its relevance to emergence of chronic disease and to therapy.
BACKGROUND:Stochastic fluctuations in the protein turnover underlie the random emergence of neural precursor cells from initially homogenous cell population. If stochastic alteration of the levels in signal transduction networks is sufficient to spontaneously alter a phenotype, can it cause a sporad...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-06-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2692004?pdf=render |