Stiffness-matched biomaterial implants for cell delivery: clinical, intraoperative ultrasound elastography provides a ‘target’ stiffness for hydrogel synthesis in spinal cord injury

Safe hydrogel delivery requires stiffness-matching with host tissues to avoid iatrogenic damage and reduce inflammatory reactions. Hydrogel-encapsulated cell delivery is a promising combinatorial approach to spinal cord injury therapy, but a lack of in vivo clinical spinal cord injury stiffness meas...

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Bibliographic Details
Main Authors: Jon Prager, Christopher F Adams, Alexander M Delaney, Guillaume Chanoit, John F Tarlton, Liang-Fong Wong, Divya M Chari, Nicolas Granger
Format: Article
Language:English
Published: SAGE Publishing 2020-07-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731420934806