Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

Abstract Background Neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker of early diagnosis and prediction for acute kidney injury (AKI). However, the current program for NGAL detection is not extensively applied in clinics due to the high expense of antibodies. Nucleic acid ap...

Full description

Bibliographic Details
Main Authors: Xiaoqian Hong, Huihui Yan, Fuan Xie, Kaiyu Wang, Qiang Wang, Huijuan Huang, Kunrong Yang, Suhong Huang, Tingting Zhao, Junkai Wang, Yunyun Chen, Kuancan Liu, Xiaopeng Lan
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Translational Medicine
Subjects:
Aptamers
NGAL protein
Acute kidney injury
Online Access:http://link.springer.com/article/10.1186/s12967-019-1955-7

Internet

http://link.springer.com/article/10.1186/s12967-019-1955-7

Similar Items