Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.

Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.

Understanding the host genetics of the immune response in retrovirus infection models could provide insights for basic HIV vaccine discovery. In Friend retrovirus (FV) infection of mice, Fv1 differentially inhibits N-tropic versus B-tropic FV infection by mediating a capsid-dependent post-entry bloc...

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Bibliographic Details
Main Authors: Kalani Halemano, Bradley S Barrett, Sam X Li, Michael S Harper, Diana S Smith, Karl J Heilman, Mario L Santiago
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3606284?pdf=render

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