Role of Pseudouridine Formation by Deg1 for Functionality of Two Glutamine Isoacceptor tRNAs

Loss of Deg1/Pus3 and concomitant elimination of pseudouridine in tRNA at positions 38 and 39 (ψ38/39) was shown to specifically impair the function of tRNAGlnUUG under conditions of temperature-induced down-regulation of wobble uridine thiolation in budding yeast and is linked to intellectual disab...

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Bibliographic Details
Main Authors: Roland Klassen, Raffael Schaffrath
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/7/1/8

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