A single-tube allele specific-polymerase chain reaction to detect T315I resistant mutation in chronic myeloid leukemia patients

A single-tube allele specific-polymerase chain reaction to detect T315I resistant mutation in chronic myeloid leukemia patients

<p>Abstract</p> <p>Background</p> <p><it>BCR-ABL </it>kinase domain (KD) mutation is the major mechanism contributing to suboptimal response to tyrosine kinase inhibitors (TKI) in <it>BCR-ABL</it>-positive chronic myeloid leukemia (CML) patients....

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Bibliographic Details
Main Authors: Auewarakul Chirayu U, Thongnoppakhun Wanna, Wongboonma Wanwisa
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/4/1/7

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