Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing

Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing

<p>Abstract</p> <p>Background</p> <p>RNA sequencing (RNA-Seq) has emerged as a powerful approach for the detection of differential gene expression with both high-throughput and high resolution capabilities possible depending upon the experimental design chosen. Multiple...

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Bibliographic Details
Main Authors: Robles José A, Qureshi Sumaira E, Stephen Stuart J, Wilson Susan R, Burden Conrad J, Taylor Jennifer M
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Genomics
Subjects:
RNA-Seq
Differential expression analysis
Sequencing depth
Replication
Experimental design
Multiplex
Online Access:http://www.biomedcentral.com/1471-2164/13/484

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