Overexpression of S100A4 as a biomarker of metastasis and recurrence in oral squamous cell carcinoma

S100A4, a biomarker of epithelial mesenchymal transition (EMT), plays an important role in invasion and metastasis by promoting cancer cell motility. In oral squamous cell carcinoma (OSCC), metastasis results in 90% of cancer associated mortality. Objective: To investigate the role of S100A4 expres...

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Bibliographic Details
Main Authors: Jayalakshmi NATARAJAN, Keith HUNTER, Vimi S MUTALIK, Raghu RADHAKRISHNAN
Format: Article
Language:English
Published: University of São Paulo 2014-10-01
Series:Journal of Applied Oral Science
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000500426&lng=en&tlng=en