Research progress in magnetic nanoparticles for magnetic resonance imaging and targeted therapy of hepatocellular carcinoma
Superparamagnetic iron oxide nanoparticles (SPIONs) are new materials that have been widely used in medical imaging, targeted therapy, magnetic hyperthermia, etc. SPIONs can be used not only for specific diagnosis of early-stage hepatocellular carcinoma (HCC), but also as a desirable targeted drug n...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Hepatology
2013-10-01
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| Series: | Linchuang Gandanbing Zazhi |
| Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=5484&ClassID=82214229 |
| Summary: | Superparamagnetic iron oxide nanoparticles (SPIONs) are new materials that have been widely used in medical imaging, targeted therapy, magnetic hyperthermia, etc. SPIONs can be used not only for specific diagnosis of early-stage hepatocellular carcinoma (HCC), but also as a desirable targeted drug nanocarrier. The properties of SPIONs as a targeted drug carrier, the principle of magnetic resonance imaging using SPIONs, and the action mechanism of SPIONs in targeting HCC are reviewed, with an emphasis on the surface modification and functionalization of SPIONs and their application in active targeted drug delivery system. It is believed that SPIONs will play a greater role in the diagnosis and treatment of HCC. |
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| ISSN: | 1001-5256 1001-5256 |