Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein

Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein

<p>Abstract</p> <p>Background</p> <p>The highly conserved nucleoprotein (NP) is an internal protein of influenza virus and is capable of inducing cross-protective immunity against different influenza A viruses, making it a main target of universal influenza vaccine. In...

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Bibliographic Details
Main Authors: Luo Jian, Zheng Dan, Zhang Wenjie, Fang Fang, Wang Hanzhong, Sun Ying, Ding Yahong, Xu Chengfei, Chen Quanjiao, Zhang Hongbo, Huang Ding, Sun Bing, Chen Ze
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Virology Journal
Subjects:
Influenza
Recombinant NP
DNA prime
Intranasal protein boost
Online Access:http://www.virologyj.com/content/9/1/286

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