Epigenetic Modifications and Head and Neck Cancer: Implications for Tumor Progression and Resistance to Therapy

Epigenetic Modifications and Head and Neck Cancer: Implications for Tumor Progression and Resistance to Therapy

Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one of the most aggressive malignancies worldwide. Despite continuous efforts to identify molecular markers for early detection, and to develop efficient treatments, the overall survival and prognosis of HNSCC patients r...

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Bibliographic Details
Main Authors: Rogerio M. Castilho, Cristiane H. Squarize, Luciana O. Almeida
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:International Journal of Molecular Sciences
Subjects:
epigenetics
HNSCC (Head and Neck Squamous Cell Carcinoma)
DNA methylation
histone modifications
microRNA
cancer stem cell
chemoresistance
acetylation
histone H3
Online Access:https://www.mdpi.com/1422-0067/18/7/1506

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