Information-analytical assessment systems for perinatal outcomes and children’s health status born by assisted reproductive technologies

• Main Authors: O. P. Kovtun, A. N. Plaxina, V. A. Makutina, N. O. Ankudinov, N. A. Zilber, O. V. Limanovskay, S. L. Sinotova
• Format: Article
• Language: Russian
• Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2020-03-01
• Series: Rossijskij Vestnik Perinatologii i Pediatrii
• Subjects: children conceived using assisted reproductive technologies (art), information and analytical systems, pregnancy outcomes, health status
• Online Access: https://www.ped-perinatology.ru/jour/article/view/1056
• ISSN: 1027-4065; 2500-2228

Purpose: To integrate clinical databases based on the information and analytical systems of medical organizations (MO) and to evaluate outcomes and health of children born by assisted reproductive technologies (ART).Research methods: To form database by integrating information and analytical systems of the medical organizations. To search and unify the data by means of freeware relational database management system (DBMS) – MySQL.Results. A prototype application for the management and support of a unified clinical database to analyze and evaluate the outcomes of ART. To compare information from individual databases of MO one need to match fields in the form of unique personal records, field validation, processing of missing data. Significant (p <0.001) differences in gestational age and anthropometric data in the databases of medical organizations (76% of full-term children from the Automated System “Regional obstetric monitoring” (AS ROM) database compared with 18% according to the IS “Register of Children requiring Early Care”) were determined by the introduction of the conception of ART, along with the presence of perinatal risk factors in children. The created software can be used to create registers of medical organizations, as well as to support clinical decision-making in forecasting, modeling outcomes and children’s health after ART, developing personalized treatment and rehabilitation programs.Conclusion. It is necessary to develop and implement information systems, to create ART registers on the basis of regional and national registers, to analyze the outcomes of the use of reproduction methods.