Microwell scaffolds for the extrahepatic transplantation of islets of Langerhans.

Microwell scaffolds for the extrahepatic transplantation of islets of Langerhans.

Allogeneic islet transplantation into the liver has the potential to restore normoglycemia in patients with type 1 diabetes. However, the suboptimal microenvironment for islets in the liver is likely to be involved in the progressive islet dysfunction that is often observed post-transplantation. Thi...

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Main Authors: Mijke Buitinga, Roman Truckenmüller, Marten A Engelse, Lorenzo Moroni, Hetty W M Ten Hoopen, Clemens A van Blitterswijk, Eelco Jp de Koning, Aart A van Apeldoorn, Marcel Karperien
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667808?pdf=render

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