Experimental validation and computational modeling of anti-influenza effects of quercetin-3-O-α-L-rhamnopyranoside from indigenous south African medicinal plant Rapanea melanophloeos

Experimental validation and computational modeling of anti-influenza effects of quercetin-3-O-α-L-rhamnopyranoside from indigenous south African medicinal plant Rapanea melanophloeos

Abstract Background Influenza A virus (IAV) is still a major health threat. The clinical manifestations of this infection are related to immune dysregulation, which causes morbidity and mortality. The usage of traditional medication with immunomodulatory properties against influenza infection has be...

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Bibliographic Details
Main Authors: Parvaneh Mehrbod, Samad Nejad Ebrahimi, Fatemeh Fotouhi, Fatemeh Eskandari, Jacobus N. Eloff, Lyndy J. McGaw, Folorunso O. Fasina
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Influenza a virus
Quercetin-3-O-α-L-rhamnopyranoside
Cytokine
Apoptosis
Molecular docking
Online Access:https://doi.org/10.1186/s12906-019-2774-3

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