Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages
Many of the beneficial and adverse effects of niacin are mediated via a G protein receptor, G protein-coupled receptor 109A/hydroxycarboxylic acid 2 receptor (GPR109A/HCA2), which is highly expressed in adipose tissue and macrophages. Here we demonstrate that immune activation increases GPR109A/HCA2...
Main Authors: | Kenneth R. Feingold, Arthur Moser, Judy K. Shigenaga, Carl Grunfeld |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520366906 |
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