Glucose deprivation in tuberous sclerosis complex-related tumors
<p>Abstract</p> <p>Background</p> <p>Cancer cells possess unique metabolic phenotypes that are determined by their underlying oncogenic pathways. Activation of the PI3K/Akt/mTOR signaling cascade promotes glycolysis and leads to glucose-dependence in tumors. In particul...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-10-01
|
| Series: | Cell & Bioscience |
| Subjects: | |
| Online Access: | http://www.cellandbioscience.com/content/1/1/34 |