Glucose deprivation in tuberous sclerosis complex-related tumors

Glucose deprivation in tuberous sclerosis complex-related tumors

<p>Abstract</p> <p>Background</p> <p>Cancer cells possess unique metabolic phenotypes that are determined by their underlying oncogenic pathways. Activation of the PI3K/Akt/mTOR signaling cascade promotes glycolysis and leads to glucose-dependence in tumors. In particul...

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Bibliographic Details
Main Authors: Jiang Xiuyun, Kenerson Heidi L, Yeung Raymond S
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Cell & Bioscience
Subjects:
mTOR
2-deoxyglucose
glycolysis
metabolism
rapamycin
ketone bodies
fatty acids
Online Access:http://www.cellandbioscience.com/content/1/1/34

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http://www.cellandbioscience.com/content/1/1/34

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