A novel approach for transcription factor analysis using SELEX with high-throughput sequencing (TFAST).

A novel approach for transcription factor analysis using SELEX with high-throughput sequencing (TFAST).

In previous work, we designed a modified aptamer-free SELEX-seq protocol (afSELEX-seq) for the discovery of transcription factor binding sites. Here, we present original software, TFAST, designed to analyze afSELEX-seq data, validated against our previously generated afSELEX-seq dataset and a model...

Full description

Bibliographic Details
Main Authors: Daniel J Reiss, Frederick M Howard, Harry L T Mobley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430675?pdf=render

Similar Items

Similar Items