Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response

Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response

<p>Abstract</p> <p>Background</p> <p>Despite advances in the understanding of diabetic retinopathy, the nature and time course of molecular changes in the retina with diabetes are incompletely described. This study characterized the functional and molecular phenotype of...

Full description

Bibliographic Details
Main Authors:	Brucklacher Robert M, Patel Kruti M, VanGuilder Heather D, Bixler Georgina V, Barber Alistair J, Antonetti David A, Lin Cheng-Mao, LaNoue Kathryn F, Gardner Thomas W, Bronson Sarah K, Freeman Willard M
Format:	Article
Language:	English
Published:	BMC 2008-06-01
Series:	BMC Medical Genomics
Online Access:	http://www.biomedcentral.com/1755-8794/1/26

Similar Items

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome
by: Kimball Scot R, et al.
Published: (2011-05-01)

Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy.
by: Heather D VanGuilder, et al.
Published: (2011-01-01)

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment
by: Sonntag William E, et al.
Published: (2011-10-01)

Targeting Neurovascular Interaction in Retinal Disorders
by: Zhongjie Fu, et al.
Published: (2020-02-01)

Retinal Neurovascular Coupling in Diabetes
by: Garhöfer Gerhard, et al.
Published: (2020-09-01)

Ex vivo models of retinal neurovascular diseases
by: Rossino, M.G
Published: (2022)

The hippocampal neuroproteome with aging and cognitive decline: past progress and future directions
by: Heather eVanGuilder, et al.
Published: (2011-05-01)

Microphysiological Neurovascular Barriers to Model the Inner Retinal Microvasculature
by: Maurissen, Thomas L., et al.
Published: (2022)

Clinical application for the preservation of phospho-proteins through in-situ tissue stabilization
by: Ding Wei, et al.
Published: (2010-11-01)

Hypoxic-Ischemic Encephalopathy: Impact on Retinal Neurovascular Integrity and Function
by: Ismail S. Zaitoun, et al.
Published: (2021-07-01)

Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion
by: Maria I. Avrutsky, et al.
Published: (2020-06-01)

Investigating Frontal Neurovascular Coupling in Response to Workplace Design-Related Stress
by: Emad Alyan, et al.
Published: (2020-01-01)

Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption.
by: Michelle Lajko, et al.
Published: (2016-01-01)

Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline
by: Heather D. VanGuilder, et al.
Published: (2011-07-01)

Editorial: Novel Therapeutic Target and Drug Development in Neurovascular Retinal Diseases
by: Zhuo Shao, et al.
Published: (2021-04-01)

Response of the neurovascular unit to brain metastatic breast cancer cells
by: János Haskó, et al.
Published: (2019-08-01)

Magnetic Resonance Imaging of Ischemia Viability Thresholds and the Neurovascular Unit
by: Philip A. Barber
Published: (2013-05-01)

Author Correction: Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion
by: Maria I. Avrutsky, et al.
Published: (2020-07-01)

Does task complexity impact the neurovascular coupling response similarly between males and females?
by: Joel S. Burma, et al.
Published: (2021-09-01)

Neurovascular Surgery : Surgical Approaches for Neurovascular Diseases
Published: (2019)

Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis.
by: Walid Albanna, et al.
Published: (2018-01-01)

Systemic treatment with erythropoietin protects the neurovascular unit in a rat model of retinal neurodegeneration.
by: Stephanie Busch, et al.
Published: (2014-01-01)

Neurovascular Surgery Surgical Approaches for Neurovascular Diseases
Published: (2019)

Exhaustive Exercise Attenuates the Neurovascular Coupling by Blunting the Pressor Response to Visual Stimulation
by: Yuji Yamaguchi, et al.
Published: (2015-01-01)

Laser Doppler Assessment of Vasomotor Axon Reflex Responsiveness to Evaluate Neurovascular Function
by: Marie Luise Kubasch, et al.
Published: (2017-08-01)

Laser Doppler Assessment of Vasomotor Axon Reflex Responsiveness to Evaluate Neurovascular Function
by: Kubasch, Marie Luise, et al.
Published: (2017)

Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration
by: Morgan Drake, et al.
Published: (2010-02-01)

Advances in Neurovascular Treatments
by: Robert M. Starke, et al.
Published: (2014-01-01)

Developments in Neurovascular Diseases and Treatments
by: Robert M. Starke, et al.
Published: (2015-01-01)

Concurrent OCT and OCT angiography of retinal neurovascular degeneration in the 5XFAD Alzheimer's disease mice
by: Kim, T.-H, et al.
Published: (2021)

An Interactive Database of Cocaine-Responsive Gene Expression
by: Willard M. Freeman, et al.
Published: (2002-01-01)

Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults.
by: Tamas Csipo, et al.
Published: (2021-01-01)

Vasculo-Neuronal Coupling and Neurovascular Coupling at the Neurovascular Unit: Impact of Hypertension
by: Jessica L. Presa, et al.
Published: (2020-09-01)

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging
by: Colleen A. Mangold, et al.
Published: (2017-07-01)

Hemifacial Spasm and Neurovascular Compression
by: Alex Y. Lu, et al.
Published: (2014-01-01)

To be or not to be a neurovascular conflict: importance of the preoperative identification of the neurovascular conflict in the trigeminal neuralgia
by: Dana Mihaela Turliuc, et al.
Published: (2016-09-01)

Synchronized Astrocytic Ca2+ Responses in Neurovascular Coupling during Somatosensory Stimulation and for the Resting State
by: Xiaochun Gu, et al.
Published: (2018-06-01)

Modeling the neurovascular niche: unbiased transcriptome analysis of the murine subventricular zone in response to hypoxic insult.
by: Qi Li, et al.
Published: (2013-01-01)

Neurovascular-modulation: A review of primary vascular responses to transcranial electrical stimulation as a mechanism of action
by: Mersedeh Bahr-Hosseini, et al.
Published: (2021-07-01)

Assessment of Neurovascular Involvement by Malignant Musculoskeletal Tumors
by: Lawrence H. Schwartz, et al.
Published: (1997-01-01)