Niclosamide Is Active In Vitro against Mycetoma Pathogens

Niclosamide Is Active In Vitro against Mycetoma Pathogens

Redox-active drugs are the mainstay of parasite chemotherapy. To assess their repurposing potential for eumycetoma, we have tested a set of nitroheterocycles and peroxides in vitro against two isolates of <i>Madurella mycetomatis</i>, the main causative agent of eumycetoma in Sudan. All...

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Bibliographic Details
Main Authors: Abdelhalim B. Mahmoud, Shereen Abd Algaffar, Wendy van de Sande, Sami Khalid, Marcel Kaiser, Pascal Mäser
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
mycetoma
<i>Madurella mycetomatis</i>
<i>Actinomadura</i>
drug repurposing
nitroimidazole
salicylanilide
Online Access:https://www.mdpi.com/1420-3049/26/13/4005

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