Bioactive PLGA/tricalcium phosphate scaffolds incorporating phytomolecule icaritin developed for calvarial defect repair in rat model

Bioactive PLGA/tricalcium phosphate scaffolds incorporating phytomolecule icaritin developed for calvarial defect repair in rat model

Background/objectives: For treatment of large bone defects challenging in orthopaedic clinics, bone graft substitutes are commonly used for the majority of surgeons. It would be proposed in the current study that our bioactive scaffolds could additionally serve as a local delivery system for therape...

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Bibliographic Details
Main Authors: Guang-Sen Shi, Ying-Ying Li, Ya-Ping Luo, Jian-Feng Jin, Yu-Xin Sun, Li-Zhen Zheng, Yu-Xiao Lai, Long Li, Guo-hui Fu, Ling Qin, Shi-Hui Chen
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Journal of Orthopaedic Translation
Subjects:
Low-temperature rapid-prototyping technology
Composite scaffold
Calvarial bone defects
Icaritin
Osteogenesis
Osteoclastogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X20300747

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http://www.sciencedirect.com/science/article/pii/S2214031X20300747

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