Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern Sudan

Summary: We conducted a cross-sectional survey to determine the prevalence of the human immunodeficiency virus (HIV) among pregnant women attending a major hospital in Kassala state, eastern Sudan. Unlinked anonymous testing of residual blood specimens, which were originally collected for other rout...

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Main Authors: Abdalla Ali Mohammed, Zahir Osman Eltahir Babiker, Awadia Khojali Mohamed Ali, Abd Alhadi Adam Hussein Adam, Eihab Ali Hassan, Husam Kamal Eldin Osman, Elbushra Ali Mohamed Herieka
Format: Article
Language:English
Published: Elsevier 2011-03-01
Series:Journal of Infection and Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034110001000
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spelling doaj-574fe4ebb0284405a10ff21e368048e12020-11-24T23:12:59ZengElsevierJournal of Infection and Public Health1876-03412011-03-01415558Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern SudanAbdalla Ali Mohammed0Zahir Osman Eltahir Babiker1Awadia Khojali Mohamed Ali2Abd Alhadi Adam Hussein Adam3Eihab Ali Hassan4Husam Kamal Eldin Osman5Elbushra Ali Mohamed Herieka6Department of Obstetrics and Gynaecology, Faculty of Medicine & Health Sciences, University of Kassala, Kassala, SudanDepartment of Infectious Diseases & Tropical Medicine, North Manchester General Hospital, Manchester M8 5RB, United Kingdom; Corresponding author.Department of Obstetrics and Gynaecology, Faculty of Medicine & Health Sciences, University of Kassala, Kassala, SudanBlood Bank Directorate, Kassala State Ministry of Health, Kassala, SudanSudan National AIDS Control Programme, Federal Ministry of Health, Khartoum, SudanBirmingham HPA Laboratory, Heart of England Foundation NHS Trust, Bordesely Green East, Birmingham B9 5SS, United KingdomDepartment of Genitourinary Medicine, Royal Bournemouth Hospital, Castle Lane East, Bournemouth BH7 7DW, United KingdomSummary: We conducted a cross-sectional survey to determine the prevalence of the human immunodeficiency virus (HIV) among pregnant women attending a major hospital in Kassala state, eastern Sudan. Unlinked anonymous testing of residual blood specimens, which were originally collected for other routine clinical purposes, was performed using rapid immunochromatographic assays. In total, 430 residual blood specimens were consecutively collected over a 6-week period (April–May 2010). Specimens from the antenatal clinic (ANC) constituted 50.7% (218/430) of the total whereas specimens from the labour ward accounted for the remaining 49.3% (212/430). The median age of pregnant women was 29 years (range 16–40). The prevalence of HIV-1 infection was 0.23% (1/430) [95% confidence interval = 0.01–1.29%]. The only reactive specimen came from a 20-year-old ANC attendee. We report low HIV prevalence among pregnant women in eastern Sudan but further research is needed to confirm our findings. An integrated framework to diagnose and treat maternal HIV infection should be developed in order to prevent transmission to infants. Keywords: HIV, Prevalence, Pregnancy, Eastern Sudanhttp://www.sciencedirect.com/science/article/pii/S1876034110001000
collection DOAJ
language English
format Article
sources DOAJ
author Abdalla Ali Mohammed
Zahir Osman Eltahir Babiker
Awadia Khojali Mohamed Ali
Abd Alhadi Adam Hussein Adam
Eihab Ali Hassan
Husam Kamal Eldin Osman
Elbushra Ali Mohamed Herieka
spellingShingle Abdalla Ali Mohammed
Zahir Osman Eltahir Babiker
Awadia Khojali Mohamed Ali
Abd Alhadi Adam Hussein Adam
Eihab Ali Hassan
Husam Kamal Eldin Osman
Elbushra Ali Mohamed Herieka
Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern Sudan
Journal of Infection and Public Health
author_facet Abdalla Ali Mohammed
Zahir Osman Eltahir Babiker
Awadia Khojali Mohamed Ali
Abd Alhadi Adam Hussein Adam
Eihab Ali Hassan
Husam Kamal Eldin Osman
Elbushra Ali Mohamed Herieka
author_sort Abdalla Ali Mohammed
title Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern Sudan
title_short Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern Sudan
title_full Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern Sudan
title_fullStr Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern Sudan
title_full_unstemmed Seroprevalence of the human immunodeficiency virus (HIV) among pregnant women in eastern Sudan
title_sort seroprevalence of the human immunodeficiency virus (hiv) among pregnant women in eastern sudan
publisher Elsevier
series Journal of Infection and Public Health
issn 1876-0341
publishDate 2011-03-01
description Summary: We conducted a cross-sectional survey to determine the prevalence of the human immunodeficiency virus (HIV) among pregnant women attending a major hospital in Kassala state, eastern Sudan. Unlinked anonymous testing of residual blood specimens, which were originally collected for other routine clinical purposes, was performed using rapid immunochromatographic assays. In total, 430 residual blood specimens were consecutively collected over a 6-week period (April–May 2010). Specimens from the antenatal clinic (ANC) constituted 50.7% (218/430) of the total whereas specimens from the labour ward accounted for the remaining 49.3% (212/430). The median age of pregnant women was 29 years (range 16–40). The prevalence of HIV-1 infection was 0.23% (1/430) [95% confidence interval = 0.01–1.29%]. The only reactive specimen came from a 20-year-old ANC attendee. We report low HIV prevalence among pregnant women in eastern Sudan but further research is needed to confirm our findings. An integrated framework to diagnose and treat maternal HIV infection should be developed in order to prevent transmission to infants. Keywords: HIV, Prevalence, Pregnancy, Eastern Sudan
url http://www.sciencedirect.com/science/article/pii/S1876034110001000
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