Autophagy Protects the Blood-Brain Barrier Through Regulating the Dynamic of Claudin-5 in Short-Term Starvation

Autophagy Protects the Blood-Brain Barrier Through Regulating the Dynamic of Claudin-5 in Short-Term Starvation

The blood-brain barrier (BBB) is essential for the exchange of nutrient and ions to maintain the homeostasis of central nervous system (CNS). BBB dysfunction is commonly associated with the disruption of endothelial tight junctions and excess permeability, which results in various CNS diseases. Ther...

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Bibliographic Details
Main Authors: Zhenguo Yang, Chunnian Huang, Yongfu Wu, Bing Chen, Wenqing Zhang, Jingjing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Physiology
Subjects:
blood-brain barrier
claudin-5
permeability
starvation
autophagy
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00002/full

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