Light sheet microscopy for single molecule tracking in living tissue.
Single molecule observation in cells and tissue allows the analysis of physiological processes with molecular detail, but it still represents a major methodological challenge. Here we introduce a microscopic technique that combines light sheet optical sectioning microscopy and ultra sensitive high-s...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2909143?pdf=render |