Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift

Stem cells are considered the origin of neoplasms in general, and malignant tumours in particular, and the stage at which the stem cells stop their differentiation determines the degree of malignancy. However, there is increasing evidence supporting an alternative paradigm. Tumours may develop by de...

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Bibliographic Details
Main Authors: Helge L. Waldum, Kjell Öberg, Øystein F. Sørdal, Arne K. Sandvik, Bjørn I. Gustafsson, Patricia Mjønes, Reidar Fossmark
Format: Article
Language:English
Published: SAGE Publishing 2018-05-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284818775054