Treatment with aliskiren ameliorates tacrolimus-induced nephrotoxicity in rats

Introduction: Tacrolimus is frequently used as immunosuppressive agent in organ transplantation but its clinical use is limited due to its marked nephrotoxicity. Materials and methods: Male Wistar albino rats weighing 150–200 g (10–12 weeks old) were used. Animals were divided into four groups. Grou...

Full description

Bibliographic Details
Main Authors: Naif O Al-Harbi, Faisal Imam, Mohammed M Al-Harbi, Muzaffar Iqbal, Ahmed Nadeem, Othman A Al-Shahrah, Hesham M Korashy, Khalid A Al-Hosaini, Mukhtar Ahmed, Saleh Bahashwar
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320314530178