Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial–mesenchymal transition
Pancreatic ductal adenocarcinoma is one of the most lethal cancers. The Hippo pathway is involved in tumorigenesis and remodeling of tumor microenvironments. Hypoxia exists in the microenvironment of solid tumors, including pancreatic ductal adenocarcinoma and plays a vital role in tumor progression...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-04-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317691684 |