A High-Performance Liquid Chromatography Assay Method for the Determination of Lidocaine in Human Serum

A High-Performance Liquid Chromatography Assay Method for the Determination of Lidocaine in Human Serum

Here we report on the development of a selective and sensitive high-performance liquid chromatographic method for the determination of lidocaine in human serum. The extraction of lidocaine and procainamide (internal standard) from serum (0.25 mL) was achieved using diethyl ether under alkaline condi...

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Bibliographic Details
Main Authors: Hamdah M. Al Nebaihi, Matthew Primrose, James S. Green, Dion R. Brocks
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Pharmaceutics
Subjects:
lidocaine
pharmacokinetics
ultraviolet detection
Online Access:https://www.mdpi.com/1999-4923/9/4/52

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