Rapid normalization of platelet hemostasis in patients with arterial hypertension and metabolic syndrome

• Main Authors: I. N. Medvedev, A. V. Plotnikov, T. A. Kumova
• Format: Article
• Language: Russian
• Published: «FIRMA «SILICEA» LLC 2008-04-01
• Series: Российский кардиологический журнал
• Subjects: arterial hypertension; metabolic syndrome; platelets; valsartan; pioglar; hypocaloric diet; physical exercise
• Online Access: https://russjcardiol.elpub.ru/jour/article/view/1541

The study aimed at identifying rapid methods of platelet (PL) hemostasis normalization in patients with arterial hypertension (AH) and metabolic syndrome (MS). Three-month therapy course, including hypocaloric diet, dosed physical exercise, pioglar and valsartan, was administered to 35patients with AH and MS. Plasma and PL lipid peroxidation dynamics, blood and PL antioxidant potential, PL hemostasis parameters were assessed. Statistical analysis included Student's t-test. Three-month complex therapy normalized primary hemostasis and reduced peroxidation syndrome in AH and MS patients. Longer treatment will strengthen the achieved beneficial effect.