Pluripotency gene network dynamics: System views from parametric analysis.

Pluripotency gene network dynamics: System views from parametric analysis.

Multiple experimental data demonstrated that the core gene network orchestrating self-renewal and differentiation of mouse embryonic stem cells involves activity of Oct4, Sox2 and Nanog genes by means of a number of positive feedback loops among them. However, recent studies indicated that the archi...

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Main Authors: Ilya R Akberdin, Nadezda A Omelyanchuk, Stanislav I Fadeev, Natalya E Leskova, Evgeniya A Oschepkova, Fedor V Kazantsev, Yury G Matushkin, Dmitry A Afonnikov, Nikolay A Kolchanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5875786?pdf=render

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