A case of lipoma, calcification, and brain malformations in the midline of the skull

• Main Authors: Hideto Kanazawa, MD, Kenji Gonda, MD, PhD, Takamitsu Tamura, MD, PhD, Seiichi Takenoshita, MD, PhD
• Format: Article
• Language: English
• Published: Elsevier 2021-09-01
• Series: Radiology Case Reports
• Subjects: Cranial neural crest cells; Malformation; Symmetry; Pericallosal lipoma
• Online Access: http://www.sciencedirect.com/science/article/pii/S193004332100368X
• ISSN: 1930-0433

Few cases of pericallosal lipoma with several other lesions, including specific forms of calcification and brain malformations, have been reported. We present the case of an asymptomatic 83-year-old man with a pericallosal lipoma with peculiar symmetrical morphology in the midline of the skull. We posit that the lesions began forming in the very early embryonic period and were closely associated with the cranial neural crest cells. We report the neuroradiological findings of this characteristic lesion and discuss several literature reviews on the process of its formation.