Cancer Biomarkers Discovery of Methylation Modification With Direct High-Throughput Nanopore Sequencing

Cancer is a complex disease, driven by a combination of genetic and epigenetic alterations. DNA and RNA methylation modifications are the most common epigenetic events that play critical roles in cancer development and progression. Bisulfite converted sequencing is a widely used technique to detect...

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Bibliographic Details
Main Authors: Junjie Zhang, Shuilian Xie, Jingxiang Xu, Hui Liu, Shaogui Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.672804/full