Mesenchymal Stromal Cell Therapy in Novel Porcine Model of Diffuse Liver Damage Induced by Repeated Biliary Obstruction

Mesenchymal Stromal Cell Therapy in Novel Porcine Model of Diffuse Liver Damage Induced by Repeated Biliary Obstruction

In liver surgery, biliary obstruction can lead to secondary biliary cirrhosis, a life-threatening disease with liver transplantation as the only curative treatment option. Mesenchymal stromal cells (MSC) have been shown to improve liver function in both acute and chronic liver disease models. This s...

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Bibliographic Details
Main Authors: Lucie Vištejnová, Václav Liška, Arvind Kumar, Jana Křečková, Ondřej Vyčítal, Jan Brůha, Jan Beneš, Yaroslav Kolinko, Tereza Blassová, Zbyněk Tonar, Michaela Brychtová, Marie Karlíková, Jaroslav Racek, Hynek Mírka, Petr Hošek, Daniel Lysák, Milena Králíčková
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
secondary biliary cirrhosis
hepatectomy
pig model
mesenchymal stromal cell
quantitative histology
Online Access:https://www.mdpi.com/1422-0067/22/9/4304

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