Optimization of Bacillus subtilis cell growth effecting jiean-peptide production in fed batch fermentation using central composite design

Optimization of Bacillus subtilis cell growth effecting jiean-peptide production in fed batch fermentation using central composite design

Background: Optimization of nutrient feeding was developed to improve the growth of Bacillus subtilis in fed batch fermentation to increase the production of jiean-peptide (JAA). A central composite design (CCD) was used to obtain a model describing the relationship between glucose, total nitrogen,...

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Bibliographic Details
Main Authors: Juan Zhong, Xiaoyong Zhang, Yanli Ren, Jie Yang, Hong Tan, Jinyan Zhou
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Electronic Journal of Biotechnology
Subjects:
Bacillus subtilis ZK8
Iturin A
Response surface methodology
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345814000517

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