Systems Pharmacology Based Strategy for Q-Markers Discovery of HuangQin Decoction to Attenuate Intestinal Damage

Systems Pharmacology Based Strategy for Q-Markers Discovery of HuangQin Decoction to Attenuate Intestinal Damage

The quality control research of traditional Chinese medicine (TCM) is lagged far behind the space of progress in modernization and globalization. Thus the concept of quality marker (Q-marker) was proposed recently to guide the quality investigations of TCM. However, how to discover and validate the...

Full description

Bibliographic Details
Main Authors:	Xiao-min Dai, Dong-ni Cui, Jing Wang, Wei Zhang, Zun-jian Zhang, Feng-guo Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-03-01
Series:	Frontiers in Pharmacology
Subjects:	Q-marker systems pharmacology traditional Chinese medicine HuangQin decoction intestinal damage
Online Access:	http://journal.frontiersin.org/article/10.3389/fphar.2018.00236/full

Similar Items

Quantitative Evaluation of the Compatibility Effects of Huangqin Decoction on the Treatment of Irinotecan-Induced Gastrointestinal Toxicity Using Untargeted Metabolomics
by: Zun-Jian Zhang, et al.
Published: (2017-04-01)

Network pharmacology approach on the mechanism of Sanwu Huangqin Decoction in treating Behcet's disease
by: Yong-Zhu Piao, et al.
Published: (2020-05-01)

Effect of Sanwu Huangqin Decoction on IFN-γ and IL-17A levels in mice with Behcet's disease
by: Yong-Zhu Piao, et al.
Published: (2020-04-01)

A Historiographical Examination of Qin Shi Huang
by: Wu, Jonathan
Published: (2012)

San Wu Huangqin Decoction, a Chinese Herbal Formula, Inhibits Influenza a/PR/8/34 (H1N1) Virus Infection In Vitro and In Vivo
by: Qinhai Ma, et al.
Published: (2018-03-01)

Analysis of Antidepressant Activity of Huang-Lian Jie-Du Decoction Through Network Pharmacology and Metabolomics
by: Shu-Yue Qu, et al.
Published: (2021-03-01)

Anti-Inflammatory Effects of Huangqin Decoction on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice Through Regulation of the Gut Microbiota and Suppression of the Ras-PI3K-Akt-HIF-1α and NF-κB Pathways
by: Min-yao Li, et al.
Published: (2020-01-01)

Comparing the antidiabetic effects and chemical profiles of raw and fermented Chinese Ge-Gen-Qin-Lian decoction by integrating untargeted metabolomics and targeted analysis
by: Yan Yan, et al.
Published: (2018-10-01)

Huang-Lian Jie-Du decoction: a review on phytochemical, pharmacological and pharmacokinetic investigations
by: Yiyu Qi, et al.
Published: (2019-12-01)

Intermodule Coupling Analysis of Huang-Lian-Jie-Du Decoction on Stroke
by: Pengqian Wang, et al.
Published: (2019-11-01)

A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis
by: Zi-Long Wang, et al.
Published: (2018-01-01)

Analysis of the action mechanism of Fang Ji Huang Qi decoction in treating rheumatoid arthritis by network pharmacology
by: Yang Hu, et al.
Published: (2018-11-01)

Qin Shihuang : la historia como discurso ideológico
by: José Antonio Cervera Jiménez
Published: (2009-09-01)

Therapeutic effect of n-butanol fraction of Huang-lian-Jie-du Decoction on ulcerative colitis and its regulation on intestinal flora in colitis mice
by: Ziwen Yuan, et al.
Published: (2020-01-01)

Scutellaria baicalensis – a small plant with large pro-health biological activities
by: Wojtunik-Kulesza Karolina, et al.
Published: (2021-03-01)

GeGen QinLian decoction alleviate influenza virus infectious pneumonia through intestinal flora
by: Li Deng, et al.
Published: (2021-09-01)

HuangQi Decoction Ameliorates Renal Fibrosis via TGF-β/Smad Signaling Pathway In Vivo and In Vitro
by: Jie Zhao, et al.
Published: (2016-05-01)

HuangQi Decoction Improves Renal Tubulointerstitial Fibrosis in Mice by Inhibiting the Up-Regulation of Wnt/β-Catenin Signaling Pathway
by: Ming-Qian Jiang, et al.
Published: (2015-05-01)

Becoming Sages: Qin Song and Self-Cultivation in Late Imperial China
by: Wu, Zeyuan
Published: (2020)

Network pharmacology-based approach to investigate the mechanism of Huang-Lian-Jie-Du-Decoction for treatment of type 2 diabetes mellitus
by: Hui-Ling Li, et al.
Published: (2021-07-01)

The Traditional Chinese Medicine Compound Huangqin Qingre Chubi Capsule Inhibits the Pathogenesis of Rheumatoid Arthritis Through the CUL4B/Wnt Pathway
by: Xiao Wang, et al.
Published: (2021-08-01)

1H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug With Efficacy and a Favorable Therapeutic Window
by: Xiaowei Fu, et al.
Published: (2019-04-01)

Huang-Lian-Jie-Du Decoction Attenuates Atherosclerosis and Increases Plaque Stability in High-Fat Diet-Induced ApoE-/- Mice by Inhibiting M1 Macrophage Polarization and Promoting M2 Macrophage Polarization
by: Yinhe Cai, et al.
Published: (2021-09-01)

Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function
by: Ziwen Yuan, et al.
Published: (2019-11-01)

Effect of Huang-Lian Jie-Du Decoction on Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
by: Zhipeng Hu, et al.
Published: (2021-04-01)

Impacts of Mining and Urbanization on the Qin-Ba Mountainous Environment, China
by: Xinliang Xu, et al.
Published: (2016-05-01)

Self, the Ultimate and “others” in pre-Qin conceptions of sagehood
by: Tang, Maoqin
Published: (2019)

Metabolomic Assessment of Acute Cholestatic Injuries Induced by Thioacetamide and by Bile Duct Ligation, and the Protective Effects of Huang-Lian-Jie-Du-Decoction
by: Dan-Dan Wei, et al.
Published: (2018-05-01)

Long-Term Wu Qin Xi Exercise on Response Inhibition and Cortical Connectivity in Parkinson's Disease: Design and Implementation of a Randomized Controlled Clinical Trial
by: Zhen Wang, et al.
Published: (2021-07-01)

Deep Learning-Based Artistic Inheritance and Cultural Emotion Color Dissemination of Qin Opera
by: Yu, H.
Published: (2022)

From chromaticism to pentatonism: a convergence of ideology and practice in Qin music of the Ming and Qing dynasties.
Published: (2009)

The story of the “Qiulai” qin unraveled by radiocarbon dating, Chinese inscriptions and material characterization
by: Marie-Gabrielle Durier, et al.
Published: (2021-07-01)

社會變遷中的廣陵琴派.
Published: (2002)

Continuity and innovation in imperial inscriptions. Augustus’ Res Gestae and the Stelae of the Qin First Emperor Compared
by: Chen Xiong
Published: (2020-05-01)

SHANG YANG 商鞅 AND LEGALIST 法家 REFORM IN THE ANCIENT CHINESE STATE OF QIN 秦
by: Daniel HAITAS
Published: (2018-05-01)

A bioinformatics investigation into the pharmacological mechanisms of the effect of the Yinchenhao decoction on hepatitis C based on network pharmacology
by: Jingyuan Zhang, et al.
Published: (2020-02-01)

Multiscale analysis by nonseparable wavelet and Hilbert-Huang transform
by: Zhang, Dan
Published: (2012)

Confucian Family Education and Ideological Tradition «Tian Di Jun Qin Shi»
by: Xinzhu Zhao
Published: (2021-12-01)

El pasado para entender el futuro del Estado de Derecho chino
by: Natalia Ruiz Morato
Published: (2011-01-01)

Metrical Structure and Freedom in Qin Music of the Chinese Literati
by: Tse, Chun-Yan, et al.
Published: (2020-12-01)