New cut-off values for screening of trisomy 21, 18 and open neural tube defects (ONTD) during the second trimester in pregnant women with advanced maternal age

Abstract Background To determine whether advanced maternal age (AMA) causes changes in the maternal serum markers of Trisomy 21, 18 and open neural tube defects (ONTD) during the second trimester of pregnancy. Our research aims to develop new cut-off values for AMA in order to reduce the need for fu...

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Bibliographic Details
Main Authors: Yiming Chen, Xue Wang, Liyao Li, Sha Lu, Zhifen Zhang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:https://doi.org/10.1186/s12884-020-03464-z