Suppressor of Cytokine Signaling 3 (SOCS3) Degrades p65 and Regulate HIV-1 Replication

Human Immunodeficiency Virus-1 (HIV-1) is known to induce the expression of SOCS3 which is a negative feed-back regulator of inflammatory responses. Here, we demonstrate that reactivation of latent HIV-1 leads to degradation of SOCS3 at early time points. Interestingly, SOCS3 degradation following t...

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Bibliographic Details
Main Authors: Vikas Sood, Sneh Lata, Vishnampettai G. Ramachandran, Akhil C. Banerjea
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
p65
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00114/full