TYPE 1 DIABETES AND INSULIN RESISTANCE: ESTIMATED GLUCOSE DISPOSAL RATE AND ITS CORRELATION WITH CHRONIC COMPLICATIONS

Introduction: insulin resistance (IR) in type 1 diabetes (T1D) is associated with a higher risk of complications in these patients. The gold standard for measuring insulin sensitivity is the hyperinsulinemic-euglycemic clamp although not used in clinical practice. The estimated glucose disposal rate...

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Bibliographic Details
Main Authors: Gabriela Caeiro, Silvana A Romero Gónzalez, Jimena Itria, Jorge Waitman
Format: Article
Language:Spanish
Published: Sello Editorial Lugones 2018-07-01
Series:Revista de la Sociedad Argentina de Diabetes
Subjects:
Online Access:https://www.revistasad.com/index.php/diabetes/article/view/53
Description
Summary:Introduction: insulin resistance (IR) in type 1 diabetes (T1D) is associated with a higher risk of complications in these patients. The gold standard for measuring insulin sensitivity is the hyperinsulinemic-euglycemic clamp although not used in clinical practice. The estimated glucose disposal rate (eGDR) has been validated to estimate insulin sensitivity. Objectives: the objective was to correlate IR in T1D (eGDR), with macro and microvascular complications in patients assisted in a Diabetology Service. Materials and methods: we performed a cross-sectional study. The eGDR was calculated using HbA1c, waist circumference, and hypertensive status.
ISSN:0325-5247
2346-9420