Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis
Silicosis, a type of lung inflammation and fibrosis caused by long-term inhalation of SiO2 particles, lacks effective treatment currently. Based on the results of our previous animal experiments, in lungs of SiO2-induced silicosis rats, a large number of lymphatic vessels are generated in the early...
Main Authors: | Jinsong Zhang, Jie Cui, Xinying Li, Xiaohui Hao, Lingli Guo, Hongli Wang, Heliang Liu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-07-01
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Series: | Ecotoxicology and Environmental Safety |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651321003687 |
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