MUTATIONS IN 1700 BP FRAGMENT OF RPOB GENE OF MULTI-DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS ISOLATE

MUTATIONS IN 1700 BP FRAGMENT OF RPOB GENE OF MULTI-DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS ISOLATE

This research aimed to amplify a 1700 bp fragment of rpoB gene of multidrug resistance M. tuberculosis (MDR-TB) isolate and determine types of mutation beyond the core region (hot-spot region). DNA sequencing studies indicate that more than 95% of rifampin-resistant M. tuberculosis strains have muta...

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Bibliographic Details
Main Authors: Chandra Yowani, I K. Sukardika, I N. Mantik-Astawa, I K. Junitha
Format: Article
Language:English
Published: Universitas Udayana 2013-01-01
Series:Indonesia Journal of Biomedical Science
Subjects:
m.tuberculosis
rifampicin resistance
mdr-tb
Online Access:https://ijbs-udayana.org/index.php/ijbs/article/view/101

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