Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections
Although enterovirus D68 poses a major global threat to children, neither vaccines nor therapeutics are currently available. Using Cryo-EM, Zhang et al. show that two murine-derived monoclonal antibodies with therapeutic efficacy neutralize virions via binding to the canyon region, creating steric h...
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Bibliographic Details
| Main Authors: |
Chao Zhang,
Cong Xu,
Wenlong Dai,
Yifan Wang,
Zhi Liu,
Xueyang Zhang,
Xuesong Wang,
Haikun Wang,
Sitang Gong,
Yao Cong,
Zhong Huang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2021-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-23199-5
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