Apolipoprotein M overexpression through adeno‐associated virus gene transfer improves insulin secretion and insulin sensitivity in Goto‐Kakizaki rats

Apolipoprotein M overexpression through adeno‐associated virus gene transfer improves insulin secretion and insulin sensitivity in Goto‐Kakizaki rats

Abstract Aims/Objective The development of type 2 diabetes is a result of insulin resistance in various tissues, including skeletal muscle and liver. Apolipoprotein M (ApoM) plays an important role in the function of high‐density lipoprotein, and also affects hepatic lipid and glucose metabolism. In...

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Bibliographic Details
Main Authors: Yang Yu, Jun Zhang, Shuang Yao, Lili Pan, Guanghua Luo, Ning Xu
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Journal of Diabetes Investigation
Subjects:
Apolipoprotein M
Diabetes
Insulin sensitivity
Online Access:https://doi.org/10.1111/jdi.13261

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