An HPLC-UV method for the measurement of permeability of marker drugs in the Caco-2 cell assay

An HPLC-UV method for the measurement of permeability of marker drugs in the Caco-2 cell assay

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The Caco-2 cell line has been used as a model to predict the in vitro permeability of the human intestinal barrier. The predictive potential of the assay relies on an appropriate in-house validation of the method. The objective of the present study was to develop a single HPLC-UV method for the iden...

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Bibliographic Details
Main Authors:	J.M. Kratz, M.R. Teixeira, L.S. Koester, C.M.O. Simões
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2011-06-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Caco-2 HPLC-UV Marker drugs Permeability
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000600006&lng=en&tlng=en

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