The directed differentiation of human iPS cells into kidney podocytes.

The loss of glomerular podocytes is a key event in the progression of chronic kidney disease resulting in proteinuria and declining function. Podocytes are slow cycling cells that are considered terminally differentiated. Here we provide the first report of the directed differentiation of induced pl...

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Bibliographic Details
Main Authors: Bi Song, Alexandra M Smink, Christina V Jones, Judy M Callaghan, Stephen D Firth, Claude A Bernard, Andrew L Laslett, Peter G Kerr, Sharon D Ricardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460883?pdf=render